null

SMILES: CCC1CN(Cc2ccccc2)c2cc(ccc2N1C(C)=O)C1=CCNCC1

InChI Key: InChIKey=GRXHTVINFFTUNX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50455512 (CHEMBL4206478) Show SMILES CCC1CN(Cc2ccccc2)c2cc(ccc2N1C(C)=O)C1=CCNCC1 |t:25| Show InChI InChI=1S/C24H29N3O/c1-3-22-17-26(16-19-7-5-4-6-8-19)24-15-21(20-11-13-25-14-12-20)9-10-23(24)27(22)18(2)28/h4-11,15,22,25H,3,12-14,16-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Displacement of (+)-JQ1 from 6H-Thr BRD4 Y97A mutant BD2 (unknown origin) after 30 mins by TR-FRET assay				J Med Chem 61: 4317-4334 (2018) Article DOI: 10.1021/acs.jmedchem.7b01666 BindingDB Entry DOI: 10.7270/Q27H1N6W
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50455512 (CHEMBL4206478) Show SMILES CCC1CN(Cc2ccccc2)c2cc(ccc2N1C(C)=O)C1=CCNCC1 |t:25| Show InChI InChI=1S/C24H29N3O/c1-3-22-17-26(16-19-7-5-4-6-8-19)24-15-21(20-11-13-25-14-12-20)9-10-23(24)27(22)18(2)28/h4-11,15,22,25H,3,12-14,16-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assay				J Med Chem 61: 4317-4334 (2018) Article DOI: 10.1021/acs.jmedchem.7b01666 BindingDB Entry DOI: 10.7270/Q27H1N6W
					More data for this Ligand-Target Pair