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BDBM50455964 CHEMBL542090

SMILES: Cl.CCCCCOc1ccccc1C(=O)NC(=O)NC1CC2CCC(C1)N2C

InChI Key: InChIKey=YLAFRLFNGBVNLY-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455964   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50455964
PNG
(CHEMBL542090)
Show SMILES Cl.CCCCCOc1ccccc1C(=O)NC(=O)NC1CC2CCC(C1)N2C |TLB:18:19:26:22.23|
Show InChI InChI=1S/C21H31N3O3.ClH/c1-3-4-7-12-27-19-9-6-5-8-18(19)20(25)23-21(26)22-15-13-16-10-11-17(14-15)24(16)2;/h5-6,8-9,15-17H,3-4,7,10-14H2,1-2H3,(H2,22,23,25,26);1H
PDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/a 32n/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.

J Med Chem 35: 1515-20 (1992)


BindingDB Entry DOI: 10.7270/Q24B32SK
More data for this
Ligand-Target Pair