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BDBM50456135 CHEMBL4217381

SMILES: CC(C)c1cn2cccc(C(=O)NCC3CCN(CC4(O)CCCCC4)CC3)c2n1

InChI Key: InChIKey=BJXMSENPVFIAQH-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456135   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))		BDBM50456135
PNG
(CHEMBL4217381)
Show SMILES CC(C)c1cn2cccc(C(=O)NCC3CCN(CC4(O)CCCCC4)CC3)c2n1
Show InChI InChI=1S/C24H36N4O2/c1-18(2)21-16-28-12-6-7-20(22(28)26-21)23(29)25-15-19-8-13-27(14-9-19)17-24(30)10-4-3-5-11-24/h6-7,12,16,18-19,30H,3-5,8-11,13-15,17H2,1-2H3,(H,25,29)
UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.300n/an/an/an/a



Suven Life Sciences Limited

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human 5-HT4E receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...

J Med Chem 61: 4993-5008 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00457
BindingDB Entry DOI: 10.7270/Q21R6T32
More data for this
Ligand-Target Pair