BDBM50456136 CHEMBL4211044

SMILES: CC(C)c1cn2cccc(C(=O)NCC3CCN(CC4(O)CCOCC4)CC3)c2n1

InChI Key: InChIKey=FQXMKRKLRPHQMF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50456136 (CHEMBL4211044) Show SMILES CC(C)c1cn2cccc(C(=O)NCC3CCN(CC4(O)CCOCC4)CC3)c2n1 Show InChI InChI=1S/C23H34N4O3/c1-17(2)20-15-27-9-3-4-19(21(27)25-20)22(28)24-14-18-5-10-26(11-6-18)16-23(29)7-12-30-13-8-23/h3-4,9,15,17-18,29H,5-8,10-14,16H2,1-2H3,(H,24,28)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Suven Life Sciences Limited Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT4E receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...				J Med Chem 61: 4993-5008 (2018) Article DOI: 10.1021/acs.jmedchem.8b00457 BindingDB Entry DOI: 10.7270/Q21R6T32
					More data for this Ligand-Target Pair