BDBM50456420 CHEMBL4216081

SMILES: OC(Cn1c2cc(Cl)ccc2oc1=O)c1ccc(F)cc1

InChI Key: InChIKey=KWTHSCVNAKPOGD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50456420 (CHEMBL4216081) Show SMILES OC(Cn1c2cc(Cl)ccc2oc1=O)c1ccc(F)cc1 Show InChI InChI=1S/C15H11ClFNO3/c16-10-3-6-14-12(7-10)18(15(20)21-14)8-13(19)9-1-4-11(17)5-2-9/h1-7,13,19H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs				Eur J Med Chem 138: 199-211 (2017) Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012
					More data for this Ligand-Target Pair