BDBM50456428 CHEMBL4209018

SMILES: COc1cccc(CNC(=O)n2c3cc(Cl)ccc3oc2=O)c1

InChI Key: InChIKey=RRYPFZBWRGCZKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50456428 (CHEMBL4209018) Show SMILES COc1cccc(CNC(=O)n2c3cc(Cl)ccc3oc2=O)c1 Show InChI InChI=1S/C16H13ClN2O4/c1-22-12-4-2-3-10(7-12)9-18-15(20)19-13-8-11(17)5-6-14(13)23-16(19)21/h2-8H,9H2,1H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs				Eur J Med Chem 138: 199-211 (2017) Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012
					More data for this Ligand-Target Pair