BDBM50456530 CHEMBL4210871

SMILES: Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1ccc(F)cc1

InChI Key: InChIKey=DJTGHRYGMPWMJC-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50456530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50456530 (CHEMBL4210871) Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C19H16FNO5S2/c1-12-17(27-19(21-12)13-2-4-14(20)5-3-13)10-26-15-6-8-16(9-7-15)28(24,25)11-18(22)23/h2-9H,10-11H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	191	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay				Eur J Med Chem 138: 458-479 (2017) Article DOI: 10.1016/j.ejmech.2017.07.001 BindingDB Entry DOI: 10.7270/Q269765Z
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50456530 (CHEMBL4210871) Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C19H16FNO5S2/c1-12-17(27-19(21-12)13-2-4-14(20)5-3-13)10-26-15-6-8-16(9-7-15)28(24,25)11-18(22)23/h2-9H,10-11H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Guangdong Pharmaceutical University Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARdelta LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay				Eur J Med Chem 164: 352-365 (2019) Article DOI: 10.1016/j.ejmech.2018.12.069
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50456530 (CHEMBL4210871) Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C19H16FNO5S2/c1-12-17(27-19(21-12)13-2-4-14(20)5-3-13)10-26-15-6-8-16(9-7-15)28(24,25)11-18(22)23/h2-9H,10-11H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	253	n/a	n/a	n/a	n/a
Guangdong Pharmaceutical University Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor expressed in CHO cells by Fluo 4-AM dye based FLIPR assay				Eur J Med Chem 164: 352-365 (2019) Article DOI: 10.1016/j.ejmech.2018.12.069
					More data for this Ligand-Target Pair