BDBM50456553 CHEMBL4212170

SMILES: COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1

InChI Key: InChIKey=RNOZYRXFDFHXAN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50456553 (CHEMBL4212170) Show SMILES COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1 Show InChI InChI=1S/C24H24O6S/c1-16-11-21(29-3)12-17(2)24(16)19-6-4-5-18(13-19)14-30-20-7-9-22(10-8-20)31(27,28)15-23(25)26/h4-13H,14-15H2,1-3H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay				Eur J Med Chem 138: 458-479 (2017) Article DOI: 10.1016/j.ejmech.2017.07.001 BindingDB Entry DOI: 10.7270/Q269765Z
					More data for this Ligand-Target Pair