BDBM50456766 CHEMBL4209967

SMILES: [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(\C=C\C(=O)OCC)=C[C@]21C)C(=O)OC

InChI Key: InChIKey=YXFJJLOXDRZLKA-VXNOPPCUSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50456766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50456766 (CHEMBL4209967) Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(\C=C\C(=O)OCC)=C[C@]21C)C(=O)OC |r,c:39,t:15| Show InChI InChI=1S/C36H52O5/c1-10-41-28(37)14-11-23-21-33(6)26(32(4,5)29(23)38)15-16-35(8)27(33)13-12-24-25-22-31(2,3)17-19-36(25,30(39)40-9)20-18-34(24,35)7/h11-12,14,21,25-27H,10,13,15-20,22H2,1-9H3/b14-11+/t25-,26-,27+,33-,34+,35+,36-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of IFN-gamma stimulated STAT3 (unknown origin) expressed in human HeLa cells after 6 hrs by luciferase reporter gene assay				J Nat Prod 80: 2276-2283 (2017) Article DOI: 10.1021/acs.jnatprod.7b00271 BindingDB Entry DOI: 10.7270/Q2VX0K32
					More data for this Ligand-Target Pair
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM50456766 (CHEMBL4209967) Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(\C=C\C(=O)OCC)=C[C@]21C)C(=O)OC |r,c:39,t:15| Show InChI InChI=1S/C36H52O5/c1-10-41-28(37)14-11-23-21-33(6)26(32(4,5)29(23)38)15-16-35(8)27(33)13-12-24-25-22-31(2,3)17-19-36(25,30(39)40-9)20-18-34(24,35)7/h11-12,14,21,25-27H,10,13,15-20,22H2,1-9H3/b14-11+/t25-,26-,27+,33-,34+,35+,36-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assay				J Nat Prod 80: 2276-2283 (2017) Article DOI: 10.1021/acs.jnatprod.7b00271 BindingDB Entry DOI: 10.7270/Q2VX0K32
					More data for this Ligand-Target Pair