BDBM50456832 CHEMBL4207323

SMILES: CC(C)Oc1ccc2c(c1)oc1cc(Cn3ccnc3)ccc1c2=O

InChI Key: InChIKey=FCILIVCCYYJYBF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50456832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM50456832 (CHEMBL4207323) Show SMILES CC(C)Oc1ccc2c(c1)oc1cc(Cn3ccnc3)ccc1c2=O Show InChI InChI=1S/C20H18N2O3/c1-13(2)24-15-4-6-17-19(10-15)25-18-9-14(3-5-16(18)20(17)23)11-22-8-7-21-12-22/h3-10,12-13H,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPTLC analysis				Eur J Med Chem 139: 60-67 (2017) Article DOI: 10.1016/j.ejmech.2017.07.078 BindingDB Entry DOI: 10.7270/Q2BZ68NG
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (Homo sapiens (Human))	BDBM50456832 (CHEMBL4207323) Show SMILES CC(C)Oc1ccc2c(c1)oc1cc(Cn3ccnc3)ccc1c2=O Show InChI InChI=1S/C20H18N2O3/c1-13(2)24-15-4-6-17-19(10-15)25-18-9-14(3-5-16(18)20(17)23)11-22-8-7-21-12-22/h3-10,12-13H,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate after 30 mins by HPTLC analysis				Eur J Med Chem 139: 60-67 (2017) Article DOI: 10.1016/j.ejmech.2017.07.078 BindingDB Entry DOI: 10.7270/Q2BZ68NG
					More data for this Ligand-Target Pair