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BDBM50457338 CHEMBL4216411

SMILES: [#7]S(=O)(=O)c1ccc(-[#6]-[#6]-[#7]-[#6](=[Se;v2])-[#7]-c2cccc(c2)C(F)(F)F)cc1

InChI Key: InChIKey=QXZHBTKZNJXXJP-UHFFFAOYSA-N

Data: 4 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50457338
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50457338 (CHEMBL4216411) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stoppe...				ACS Med Chem Lett 8: 963-968 (2017) Article DOI: 10.1021/acsmedchemlett.7b00280 BindingDB Entry DOI: 10.7270/Q2TT4TKD
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM50457338 (CHEMBL4216411) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 9 catalytic domain preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol...				ACS Med Chem Lett 8: 963-968 (2017) Article DOI: 10.1021/acsmedchemlett.7b00280 BindingDB Entry DOI: 10.7270/Q2TT4TKD
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50457338 (CHEMBL4216411) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stoppe...				ACS Med Chem Lett 8: 963-968 (2017) Article DOI: 10.1021/acsmedchemlett.7b00280 BindingDB Entry DOI: 10.7270/Q2TT4TKD
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50457338 (CHEMBL4216411) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	929	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stoppe...				ACS Med Chem Lett 8: 963-968 (2017) Article DOI: 10.1021/acsmedchemlett.7b00280 BindingDB Entry DOI: 10.7270/Q2TT4TKD
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair