BDBM50457793 CHEMBL4203663

SMILES: COc1ccc(cc1)-n1cc(NC(=O)Cn2ccc3ccccc23)cn1

InChI Key: InChIKey=XQDFLJWQHIMKDW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50457793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Mus musculus)	BDBM50457793 (CHEMBL4203663) Show SMILES COc1ccc(cc1)-n1cc(NC(=O)Cn2ccc3ccccc23)cn1 Show InChI InChI=1S/C20H18N4O2/c1-26-18-8-6-17(7-9-18)24-13-16(12-21-24)22-20(25)14-23-11-10-15-4-2-3-5-19(15)23/h2-13H,14H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of full-length GST-tagged mouse BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...				Bioorg Med Chem Lett 28: 2382-2390 (2018) Article DOI: 10.1016/j.bmcl.2018.06.028 BindingDB Entry DOI: 10.7270/Q2TM7DQ9
					More data for this Ligand-Target Pair