BDBM50457877 CHEMBL4215615

SMILES: C[C@H](C(=O)Nc1nc(C)c([nH]1)-c1ccc(Cl)c(c1)S(=O)(=O)NCCO)c1ccc(Cl)cc1

InChI Key: InChIKey=HQKUBQPEPHLGAZ-LBPRGKRZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457877 (CHEMBL4215615) Show SMILES C[C@H](C(=O)Nc1nc(C)c([nH]1)-c1ccc(Cl)c(c1)S(=O)(=O)NCCO)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C21H22Cl2N4O4S/c1-12(14-3-6-16(22)7-4-14)20(29)27-21-25-13(2)19(26-21)15-5-8-17(23)18(11-15)32(30,31)24-9-10-28/h3-8,11-12,24,28H,9-10H2,1-2H3,(H2,25,26,27,29)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457877 (CHEMBL4215615) Show SMILES C[C@H](C(=O)Nc1nc(C)c([nH]1)-c1ccc(Cl)c(c1)S(=O)(=O)NCCO)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C21H22Cl2N4O4S/c1-12(14-3-6-16(22)7-4-14)20(29)27-21-25-13(2)19(26-21)15-5-8-17(23)18(11-15)32(30,31)24-9-10-28/h3-8,11-12,24,28H,9-10H2,1-2H3,(H2,25,26,27,29)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair