BDBM50458740 CHEMBL4211255

SMILES: CS(=O)(=O)C1(CCCCC1)c1cc(nc(n1)N1CCOCC1)-c1cnc(N)cc1C(F)(F)F

InChI Key: InChIKey=PEAIAQIDLBELBZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50458740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110α/p85α (Homo sapiens (Human))	BDBM50458740 (CHEMBL4211255) Show SMILES CS(=O)(=O)C1(CCCCC1)c1cc(nc(n1)N1CCOCC1)-c1cnc(N)cc1C(F)(F)F Show InChI InChI=1S/C21H26F3N5O3S/c1-33(30,31)20(5-3-2-4-6-20)17-12-16(27-19(28-17)29-7-9-32-10-8-29)14-13-26-18(25)11-15(14)21(22,23)24/h11-13H,2-10H2,1H3,(H2,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Haiyan Pharmaceutical Technology Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...				ACS Med Chem Lett 9: 719-724 (2018) Article DOI: 10.1021/acsmedchemlett.8b00167 BindingDB Entry DOI: 10.7270/Q21V5HK8
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