BDBM50458750 CHEMBL4210320

SMILES: CS(=O)(=O)Cc1cc(nc(n1)N1CCOCC1)-c1cnc(N)cc1C(F)(F)F

InChI Key: InChIKey=IPAWIEAHHPWPAU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110α/p85α (Homo sapiens (Human))	BDBM50458750 (CHEMBL4210320) Show SMILES CS(=O)(=O)Cc1cc(nc(n1)N1CCOCC1)-c1cnc(N)cc1C(F)(F)F Show InChI InChI=1S/C16H18F3N5O3S/c1-28(25,26)9-10-6-13(23-15(22-10)24-2-4-27-5-3-24)11-8-21-14(20)7-12(11)16(17,18)19/h6-8H,2-5,9H2,1H3,(H2,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Haiyan Pharmaceutical Technology Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...				ACS Med Chem Lett 9: 719-724 (2018) Article DOI: 10.1021/acsmedchemlett.8b00167 BindingDB Entry DOI: 10.7270/Q21V5HK8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50458750 (CHEMBL4210320) Show SMILES CS(=O)(=O)Cc1cc(nc(n1)N1CCOCC1)-c1cnc(N)cc1C(F)(F)F Show InChI InChI=1S/C16H18F3N5O3S/c1-28(25,26)9-10-6-13(23-15(22-10)24-2-4-27-5-3-24)11-8-21-14(20)7-12(11)16(17,18)19/h6-8H,2-5,9H2,1H3,(H2,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Haiyan Pharmaceutical Technology Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4EBP1 a...				ACS Med Chem Lett 9: 719-724 (2018) Article DOI: 10.1021/acsmedchemlett.8b00167 BindingDB Entry DOI: 10.7270/Q21V5HK8
					More data for this Ligand-Target Pair