BDBM50459309 CHEMBL4211531

SMILES: N.N.COC(=O)N(O)C\C=C\P(O)(O)=O

InChI Key: InChIKey=VKPFUXZHJQCXIS-DUXPYHPUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50459309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic (Plasmodium falciparum (isolate 3D7))	BDBM50459309 (CHEMBL4211531) Show SMILES N.N.COC(=O)N(O)C\C=C\P(O)(O)=O Show InChI InChI=1S/C5H10NO6P/c1-12-5(7)6(8)3-2-4-13(9,10)11/h2,4,8H,3H2,1H3,(H2,9,10,11)/b4-2+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
George Washington University Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometry				J Med Chem 61: 8847-8858 (2018) Article DOI: 10.1021/acs.jmedchem.8b01026 BindingDB Entry DOI: 10.7270/Q2S75JZ7
					More data for this Ligand-Target Pair