BDBM50459616 CHEMBL4217798
SMILES: [H][C@@]12CC[C@@H](O)N([C@@H](Cc3ccccc3)C(=O)N(C)[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H](C)C(=O)O[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)C(\C)=C\C)C(=O)N[C@@H](CCC(=O)NCCO)C(=O)N1)C2=O
InChI Key: InChIKey=QWIPLKRRZPLLFU-VHRUOTHWSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-chymotrypsin (Bos taurus (bovine)) | BDBM50459616 (CHEMBL4217798) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of bovine pancreas alpha-chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate incubated for 15 mins followed by substrate... | J Nat Prod 81: 1928-1936 (2018) Article DOI: 10.1021/acs.jnatprod.7b01009 BindingDB Entry DOI: 10.7270/Q2Q81GP1 | |||||||||||
More data for this Ligand-Target Pair |