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SMILES: Clc1cccc2nc(OCC#C)oc(=O)c12

InChI Key: InChIKey=BRJPVFBTGOGQGN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460514   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rhomboid protease GluP


(Bacillus subtilis (strain 168))		BDBM50460514
PNG
(CHEMBL4229256)
Show SMILES Clc1cccc2nc(OCC#C)oc(=O)c12
Show InChI InChI=1S/C11H6ClNO3/c1-2-6-15-11-13-8-5-3-4-7(12)9(8)10(14)16-11/h1,3-5H,6H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.20E+3n/an/an/an/an/an/a



KU Leuven

Curated by ChEMBL


Assay Description
Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...

Bioorg Med Chem Lett 28: 1423-1427 (2018)


Article DOI: 10.1016/j.bmcl.2017.12.056
BindingDB Entry DOI: 10.7270/Q2WH2SM6
More data for this
Ligand-Target Pair