Found 25 hits for monomerid = 50460767 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Aurora kinase B
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33... |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of PLK3 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of PKCA (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of RSK2 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | <4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of Aurora A (unknown origin) using Tamra-PKAtide as substrate by fluorescence polarization assay |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | <13 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of Aurora B (unknown origin) using Tamra-PKAtide as substrate by fluorescence polarization assay |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of CHK1 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Ephrin type-B receptor 4
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of EPHB4 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of LCK (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of CDK2 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of IGF1R (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of JAK2 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of MET (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of NEK2 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Rho-associated protein kinase 2
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of ROCK2 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Testis-specific serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of TSSK2 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of AKT1 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Calcium/calmodulin-dependent protein kinase type IV
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of CAMK4 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of GSK3b (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of IKKB (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of CSNK1D (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase 3
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of MST2 (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50460767
(CHEMBL4228240)Show SMILES CCN(CCO)Cc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H22N8OS/c1-3-25(4-5-27)11-14-6-16(28-24-14)23-17-18-19-9-15(13-7-20-21-8-13)26(18)10-12(2)22-17/h6-10,27H,3-5,11H2,1-2H3,(H,20,21)(H,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) |
Bioorg Med Chem Lett 28: 1397-1403 (2018)
Article DOI: 10.1016/j.bmcl.2018.02.037
BindingDB Entry DOI: 10.7270/Q2K35X91 |
More data for this
Ligand-Target Pair | |
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