BDBM50461795 CHEMBL4228540
SMILES: [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCCC(O)=O
InChI Key: InChIKey=FQPYDDPGOROZFM-JRMIMQNLSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT) | BDBM50461795 (CHEMBL4228540) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a |
Institute of Physiology of the Czech Academy of Sciences Curated by ChEMBL | Assay Description Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ... | J Med Chem 61: 4505-4516 (2018) Article DOI: 10.1021/acs.jmedchem.8b00255 BindingDB Entry DOI: 10.7270/Q2Z03BTB | |||||||||||
More data for this Ligand-Target Pair |