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SMILES: CN1CC(=O)N2[C@@H](c3[nH]c4ccccc4c3C[C@]2(C)C1=O)c1ccc2OCOc2c1

InChI Key: InChIKey=RDIJBCYLIJAECJ-FYYLOGMGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462276   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A


(Homo sapiens (Human))		BDBM50462276
PNG
(CHEMBL4244897)
Show SMILES CN1CC(=O)N2[C@@H](c3[nH]c4ccccc4c3C[C@]2(C)C1=O)c1ccc2OCOc2c1 |r|
Show InChI InChI=1S/C23H21N3O4/c1-23-10-15-14-5-3-4-6-16(14)24-20(15)21(26(23)19(27)11-25(2)22(23)28)13-7-8-17-18(9-13)30-12-29-17/h3-9,21,24H,10-12H2,1-2H3/t21-,23-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 73n/an/an/an/an/an/a



Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital

Curated by ChEMBL


Assay Description
Inhibition of recombinant human PDE11A4 expressed in Sf9 insect cells using [3H]cGMP or [3H]cAMP as substrate after 10 mins by scintillation counting...

Eur J Med Chem 150: 742-756 (2018)


Article DOI: 10.1016/j.ejmech.2018.03.046
BindingDB Entry DOI: 10.7270/Q2JM2D83
More data for this
Ligand-Target Pair