BDBM50462305 CHEMBL4246128

SMILES: CCN(CC)CCOc1ccc(Nc2cc(Cl)nc(n2)-c2ccc(OC)cc2)cc1

InChI Key: InChIKey=XQZNFMQZYFJADZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50462305 (CHEMBL4246128) Show SMILES CCN(CC)CCOc1ccc(Nc2cc(Cl)nc(n2)-c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C23H27ClN4O2/c1-4-28(5-2)14-15-30-20-12-8-18(9-13-20)25-22-16-21(24)26-23(27-22)17-6-10-19(29-3)11-7-17/h6-13,16H,4-5,14-15H2,1-3H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	174	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using TK substrate after 1 hr by HTRF assay				Eur J Med Chem 150: 783-795 (2018) Article DOI: 10.1016/j.ejmech.2018.03.018 BindingDB Entry DOI: 10.7270/Q2959M6P
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50462305 (CHEMBL4246128) Show SMILES CCN(CC)CCOc1ccc(Nc2cc(Cl)nc(n2)-c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C23H27ClN4O2/c1-4-28(5-2)14-15-30-20-12-8-18(9-13-20)25-22-16-21(24)26-23(27-22)17-6-10-19(29-3)11-7-17/h6-13,16H,4-5,14-15H2,1-3H3,(H,25,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of Fluormone ES2 Green from full length human ER-alpha expressed in insect cells after 2 hrs by fluorescence polarization assay				Eur J Med Chem 150: 783-795 (2018) Article DOI: 10.1016/j.ejmech.2018.03.018 BindingDB Entry DOI: 10.7270/Q2959M6P
					More data for this Ligand-Target Pair