BDBM50462322 CHEMBL4248249

SMILES: COc1ccc(cc1)-c1nc(Cl)c(c(Nc2ccc(NC(=O)CN3CCCC3)cc2)n1)-c1ccccc1

InChI Key: InChIKey=INBWCZMHJMSKAB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50462322 (CHEMBL4248249) Show SMILES COc1ccc(cc1)-c1nc(Cl)c(c(Nc2ccc(NC(=O)CN3CCCC3)cc2)n1)-c1ccccc1 Show InChI InChI=1S/C29H28ClN5O2/c1-37-24-15-9-21(10-16-24)28-33-27(30)26(20-7-3-2-4-8-20)29(34-28)32-23-13-11-22(12-14-23)31-25(36)19-35-17-5-6-18-35/h2-4,7-16H,5-6,17-19H2,1H3,(H,31,36)(H,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using TK substrate after 1 hr by HTRF assay				Eur J Med Chem 150: 783-795 (2018) Article DOI: 10.1016/j.ejmech.2018.03.018 BindingDB Entry DOI: 10.7270/Q2959M6P
					More data for this Ligand-Target Pair