BDBM50462601 CHEMBL4250607

SMILES: NC(=N)Nc1ccc(cc1)C(F)C(O)=O

InChI Key: InChIKey=KMONIWBXNKKRNK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM50462601 (CHEMBL4250607) Show SMILES NC(=N)Nc1ccc(cc1)C(F)C(O)=O Show InChI InChI=1S/C9H10FN3O2/c10-7(8(14)15)5-1-3-6(4-2-5)13-9(11)12/h1-4,7H,(H,14,15)(H4,11,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.75E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Brown University Curated by ChEMBL					Assay Description Irreversible inhibition of human arginase 1 using thioarginine as substrate measured up to 360 mins by UV micro plate method				Bioorg Med Chem 26: 3939-3946 (2018) Article DOI: 10.1016/j.bmc.2018.06.015 BindingDB Entry DOI: 10.7270/Q2TX3J1K
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM50462601 (CHEMBL4250607) Show SMILES NC(=N)Nc1ccc(cc1)C(F)C(O)=O Show InChI InChI=1S/C9H10FN3O2/c10-7(8(14)15)5-1-3-6(4-2-5)13-9(11)12/h1-4,7H,(H,14,15)(H4,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.22E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Brown University Curated by ChEMBL					Assay Description Irreversible inhibition of human arginase 2 using thioarginine as substrate measured up to 360 mins by UV micro plate method				Bioorg Med Chem 26: 3939-3946 (2018) Article DOI: 10.1016/j.bmc.2018.06.015 BindingDB Entry DOI: 10.7270/Q2TX3J1K
					More data for this Ligand-Target Pair