BDBM50462613 CHEMBL4246864

SMILES: CCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)B(O)O

InChI Key: InChIKey=HCAYFQBLIJQFHP-IRXDYDNUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-1/beta type-5 (Homo sapiens (Human))	BDBM50462613 (CHEMBL4246864) Show SMILES CCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)B(O)O |r| Show InChI InChI=1S/C19H31BN2O4/c1-4-5-11-18(23)21-16(13-15-9-7-6-8-10-15)19(24)22-17(20(25)26)12-14(2)3/h6-10,14,16-17,25-26H,4-5,11-13H2,1-3H3,(H,21,23)(H,22,24)/t16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing Forestry University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...				Bioorg Med Chem 26: 3975-3981 (2018) Article DOI: 10.1016/j.bmc.2018.06.020 BindingDB Entry DOI: 10.7270/Q2Q81GQG
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