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BDBM50462780 CHEMBL4237257

SMILES: CN1CCC(COc2nc(sc2C)-c2ccccc2)CC1

InChI Key: InChIKey=VCPCJSKIRHEPQR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462780   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50462780
PNG
(CHEMBL4237257)
Show SMILES CN1CCC(COc2nc(sc2C)-c2ccccc2)CC1
Show InChI InChI=1S/C17H22N2OS/c1-13-16(20-12-14-8-10-19(2)11-9-14)18-17(21-13)15-6-4-3-5-7-15/h3-7,14H,8-12H2,1-2H3
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 220n/an/an/an/an/an/an/an/a



Heinrich Heine University D£sseldorf

Curated by ChEMBL


Assay Description
Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cell membranes

Bioorg Med Chem 26: 4034-4046 (2018)


Article DOI: 10.1016/j.bmc.2018.06.028
BindingDB Entry DOI: 10.7270/Q29026FG
More data for this
Ligand-Target Pair