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BDBM50462819 CHEMBL4241181

SMILES: Cc1sc(nc1OCc1ccc(CN2CCCCC2)cc1)-c1ccc(cc1)C#N

InChI Key: InChIKey=QKJXEZPTKNFIJJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462819   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50462819
PNG
(CHEMBL4241181)
Show SMILES Cc1sc(nc1OCc1ccc(CN2CCCCC2)cc1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H25N3OS/c1-18-23(26-24(29-18)22-11-9-19(15-25)10-12-22)28-17-21-7-5-20(6-8-21)16-27-13-3-2-4-14-27/h5-12H,2-4,13-14,16-17H2,1H3
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Article
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 450n/an/an/an/an/an/an/an/a



Heinrich Heine University D£sseldorf

Curated by ChEMBL


Assay Description
Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cell membranes

Bioorg Med Chem 26: 4034-4046 (2018)


Article DOI: 10.1016/j.bmc.2018.06.028
BindingDB Entry DOI: 10.7270/Q29026FG
More data for this
Ligand-Target Pair