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BDBM50462827 CHEMBL4239651

SMILES: CCc1sc(nc1OCCCN1CCCCC1)-c1ccc(Cl)cc1

InChI Key: InChIKey=XLIRRJABCDCGFT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462827   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50462827
PNG
(CHEMBL4239651)
Show SMILES CCc1sc(nc1OCCCN1CCCCC1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H25ClN2OS/c1-2-17-18(23-14-6-13-22-11-4-3-5-12-22)21-19(24-17)15-7-9-16(20)10-8-15/h7-10H,2-6,11-14H2,1H3
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 200n/an/an/an/an/an/an/an/a



Heinrich Heine University D£sseldorf

Curated by ChEMBL


Assay Description
Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cell membranes

Bioorg Med Chem 26: 4034-4046 (2018)


Article DOI: 10.1016/j.bmc.2018.06.028
BindingDB Entry DOI: 10.7270/Q29026FG
More data for this
Ligand-Target Pair