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SMILES: NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1cncs1

InChI Key: InChIKey=LSLKHHXTRZYALE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463130   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Myc proto-oncogene protein


(Homo sapiens (Human))		BDBM50463130
PNG
(CHEMBL4247460)
Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1cncs1
Show InChI InChI=1S/C22H14N4OS/c23-11-14-1-3-16(4-2-14)19-9-18(10-20(26-19)21-12-25-13-28-21)15-5-7-17(8-6-15)22(24)27/h1-10,12-13H,(H2,24,27)
PDB
MMDB

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n/an/a 3.00E+4n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation

Bioorg Med Chem 26: 4234-4239 (2018)


Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB
More data for this
Ligand-Target Pair