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SMILES: NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1cccc(F)c1)-c1ccc(cc1)C#N

InChI Key: InChIKey=TVESOFRCVUZDMN-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463132   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Myc proto-oncogene protein


(Homo sapiens (Human))		BDBM50463132
PNG
(CHEMBL4250683)
Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1cccc(F)c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C25H16FN3O/c26-22-3-1-2-20(12-22)24-14-21(17-8-10-19(11-9-17)25(28)30)13-23(29-24)18-6-4-16(15-27)5-7-18/h1-14H,(H2,28,30)
PDB
MMDB

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n/an/a>1.00E+5n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation

Bioorg Med Chem 26: 4234-4239 (2018)


Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB
More data for this
Ligand-Target Pair