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SMILES: CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2F)NC(=O)[C@@H](NC1=O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)CC(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CNC(C)=O

InChI Key: InChIKey=VTEYOJJPKQGFET-GYKFKOCVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463571   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Erythropoietin receptor


(Homo sapiens (Human))		BDBM50463571
PNG
(CHEMBL4244160)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2F)NC(=O)[C@@H](NC1=O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)CC(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CNC(C)=O |r|
Show InChI InChI=1S/C103H160FN29O25S3/c1-14-56(8)84-99(155)130-85(58(10)134)100(156)125-72(43-61-22-15-16-23-64(61)104)93(149)128-83(55(6)7)98(154)127-75(94(150)121-68(32-33-78(106)137)102(158)133-38-21-27-77(133)96(152)124-70(41-54(4)5)91(147)120-67(25-19-36-111-103(108)109)101(157)131(12)49-81(140)117-65(86(107)142)24-17-18-35-105)51-161-160-50-74(95(151)123-73(44-62-45-110-52-115-62)92(148)119-66(34-39-159-13)88(144)114-48-82(141)132-37-20-26-76(132)97(153)129-84)126-87(143)57(9)116-89(145)71(42-60-28-30-63(136)31-29-60)122-90(146)69(40-53(2)3)118-80(139)47-113-79(138)46-112-59(11)135/h15-16,22-23,28-31,45,52-58,65-77,83-85,134,136H,14,17-21,24-27,32-44,46-51,105H2,1-13H3,(H2,106,137)(H2,107,142)(H,110,115)(H,112,135)(H,113,138)(H,114,144)(H,116,145)(H,117,140)(H,118,139)(H,119,148)(H,120,147)(H,121,150)(H,122,146)(H,123,151)(H,124,152)(H,125,156)(H,126,143)(H,127,154)(H,128,149)(H,129,153)(H,130,155)(H4,108,109,111)/t56-,57-,58+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,83-,84-,85-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 540n/an/an/an/a



Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL


Assay Description
Agonist activity at EPO receptor in human TF1 cells assessed as induction of cell proliferation after 48 hrs by MTT assay

Bioorg Med Chem Lett 28: 3038-3041 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.004
BindingDB Entry DOI: 10.7270/Q2J67KMD
More data for this
Ligand-Target Pair