null

SMILES: Cc1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)C#N

InChI Key: InChIKey=IQFPTDKQZKIGSD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50463582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 7 (Homo sapiens (Human))	BDBM50463582 (CHEMBL4245957) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)C#N Show InChI InChI=1S/C18H20N4O2S/c1-14-2-5-17(6-3-14)25(23,24)22-10-8-16(9-11-22)21-18-7-4-15(12-19)13-20-18/h2-7,13,16H,8-11H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubate...				Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 6 (Macaca mulatta)	BDBM50463582 (CHEMBL4245957) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)C#N Show InChI InChI=1S/C18H20N4O2S/c1-14-2-5-17(6-3-14)25(23,24)22-10-8-16(9-11-22)21-18-7-4-15(12-19)13-20-18/h2-7,13,16H,8-11H2,1H3,(H,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of monkey CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubat...				Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 6 (Homo sapiens (Human))	BDBM50463582 (CHEMBL4245957) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)C#N Show InChI InChI=1S/C18H20N4O2S/c1-14-2-5-17(6-3-14)25(23,24)22-10-8-16(9-11-22)21-18-7-4-15(12-19)13-20-18/h2-7,13,16H,8-11H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...				Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 6 (Homo sapiens (Human))	BDBM50463582 (CHEMBL4245957) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)C#N Show InChI InChI=1S/C18H20N4O2S/c1-14-2-5-17(6-3-14)25(23,24)22-10-8-16(9-11-22)21-18-7-4-15(12-19)13-20-18/h2-7,13,16H,8-11H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in human CCL20-dependent cell migration incubated for 4 hrs by Diff-Quik stainin...				Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50463582 (CHEMBL4245957) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)C#N Show InChI InChI=1S/C18H20N4O2S/c1-14-2-5-17(6-3-14)25(23,24)22-10-8-16(9-11-22)21-18-7-4-15(12-19)13-20-18/h2-7,13,16H,8-11H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CCR1 expressed in CHO cells assessed as decrease in RANTES-induced reduction of forskolin-stimulated cAMP accumulation preincubat...				Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP
					More data for this Ligand-Target Pair