BDBM50463750 CHEMBL4241807

SMILES: ONC(=O)CCCCCNc1c(Nc2ccc(cc2)C(F)(F)F)c(=O)c1=O

InChI Key: InChIKey=KTWRGWSULIZQCZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50463750 (CHEMBL4241807) Show SMILES ONC(=O)CCCCCNc1c(Nc2ccc(cc2)C(F)(F)F)c(=O)c1=O Show InChI InChI=1S/C17H18F3N3O4/c18-17(19,20)10-5-7-11(8-6-10)22-14-13(15(25)16(14)26)21-9-3-1-2-4-12(24)23-27/h5-8,21-22,27H,1-4,9H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nestle Skin Health R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence method				Bioorg Med Chem Lett 28: 2985-2992 (2018) Article DOI: 10.1016/j.bmcl.2018.06.029 BindingDB Entry DOI: 10.7270/Q2M0484T
					More data for this Ligand-Target Pair