BDBM50463758 CHEMBL4250302

SMILES: COc1ccc(Nc2c(NC(C)(C)CCCCC(=O)NO)c(=O)c2=O)cc1

InChI Key: InChIKey=FCMUFMAAHVAHHR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50463758 (CHEMBL4250302) Show SMILES COc1ccc(Nc2c(NC(C)(C)CCCCC(=O)NO)c(=O)c2=O)cc1 Show InChI InChI=1S/C19H25N3O5/c1-19(2,11-5-4-6-14(23)22-26)21-16-15(17(24)18(16)25)20-12-7-9-13(27-3)10-8-12/h7-10,20-21,26H,4-6,11H2,1-3H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nestle Skin Health R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence method				Bioorg Med Chem Lett 28: 2985-2992 (2018) Article DOI: 10.1016/j.bmcl.2018.06.029 BindingDB Entry DOI: 10.7270/Q2M0484T
					More data for this Ligand-Target Pair