BDBM50463762 CHEMBL4244537

SMILES: C[C@H](Nc1c(NCCCCCC(=O)NO)c(=O)c1=O)c1ccccc1

InChI Key: InChIKey=IGBHNNFWJLUBKS-LBPRGKRZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50463762 (CHEMBL4244537) Show SMILES C[C@H](Nc1c(NCCCCCC(=O)NO)c(=O)c1=O)c1ccccc1 |r| Show InChI InChI=1S/C18H23N3O4/c1-12(13-8-4-2-5-9-13)20-16-15(17(23)18(16)24)19-11-7-3-6-10-14(22)21-25/h2,4-5,8-9,12,19-20,25H,3,6-7,10-11H2,1H3,(H,21,22)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nestle Skin Health R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence method				Bioorg Med Chem Lett 28: 2985-2992 (2018) Article DOI: 10.1016/j.bmcl.2018.06.029 BindingDB Entry DOI: 10.7270/Q2M0484T
					More data for this Ligand-Target Pair