BDBM50463768 CHEMBL4240163

SMILES: C[C@H](CCCCC(=O)NO)Nc1c(Nc2ccc(cc2)N(C)C)c(=O)c1=O

InChI Key: InChIKey=COTJKJPRKORRNQ-GFCCVEGCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50463768 (CHEMBL4240163) Show SMILES C[C@H](CCCCC(=O)NO)Nc1c(Nc2ccc(cc2)N(C)C)c(=O)c1=O |r| Show InChI InChI=1S/C19H26N4O4/c1-12(6-4-5-7-15(24)22-27)20-16-17(19(26)18(16)25)21-13-8-10-14(11-9-13)23(2)3/h8-12,20-21,27H,4-7H2,1-3H3,(H,22,24)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nestle Skin Health R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence method				Bioorg Med Chem Lett 28: 2985-2992 (2018) Article DOI: 10.1016/j.bmcl.2018.06.029 BindingDB Entry DOI: 10.7270/Q2M0484T
					More data for this Ligand-Target Pair