BDBM50464263 CHEMBL4277386

SMILES: COc1ccc(Cl)cc1OC1CN(C1)S(=O)(=O)c1ccc2cn[nH]c2c1

InChI Key: InChIKey=XEMFXFVWPTWGBK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine receptor alpha-3/beta (Homo sapiens (Human))	BDBM50464263 (CHEMBL4277386) Show SMILES COc1ccc(Cl)cc1OC1CN(C1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C17H16ClN3O4S/c1-24-16-5-3-12(18)6-17(16)25-13-9-21(10-13)26(22,23)14-4-2-11-8-19-20-15(11)7-14/h2-8,13H,9-10H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair