BDBM50464579 CHEMBL4281975

SMILES: COc1cncc(Cc2ccc(nc2)-c2ccccc2F)c1

InChI Key: InChIKey=FKUQZILZPJKQBD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM50464579 (CHEMBL4281975) Show SMILES COc1cncc(Cc2ccc(nc2)-c2ccccc2F)c1 Show InChI InChI=1S/C18H15FN2O/c1-22-15-9-14(10-20-12-15)8-13-6-7-18(21-11-13)16-4-2-3-5-17(16)19/h2-7,9-12H,8H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPTLC analysis				Eur J Med Chem 143: 591-597 (2018) Article DOI: 10.1016/j.ejmech.2017.11.018 BindingDB Entry DOI: 10.7270/Q2SF2ZTB
					More data for this Ligand-Target Pair