BDBM50464729 CHEMBL4286917

SMILES: FC(F)(F)Oc1ccc(cc1)-c1nn2c(nc(cc2=O)C(F)(F)F)s1

InChI Key: InChIKey=CXTMGFVWPPKROS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50464729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intestinal alkaline phosphatase (Homo sapiens (Human))	BDBM50464729 (CHEMBL4286917) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1nn2c(nc(cc2=O)C(F)(F)F)s1 Show InChI InChI=1S/C13H5F6N3O2S/c14-12(15,16)8-5-9(23)22-11(20-8)25-10(21-22)6-1-3-7(4-2-6)24-13(17,18)19/h1-5H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human IAP expressed in COS7 cells preincubated for 5 to 7 mins followed by CDP-star substrate addition measured after 15 to 20 mins by ...				Eur J Med Chem 144: 116-127 (2018) Article DOI: 10.1016/j.ejmech.2017.11.068 BindingDB Entry DOI: 10.7270/Q2W66PDP
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50464729 (CHEMBL4286917) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1nn2c(nc(cc2=O)C(F)(F)F)s1 Show InChI InChI=1S/C13H5F6N3O2S/c14-12(15,16)8-5-9(23)22-11(20-8)25-10(21-22)6-1-3-7(4-2-6)24-13(17,18)19/h1-5H	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human TNAP expressed in COS7 cells preincubated for 5 to 7 mins followed by CDP-star substrate addition measured after 15 to 20 mins by...				Eur J Med Chem 144: 116-127 (2018) Article DOI: 10.1016/j.ejmech.2017.11.068 BindingDB Entry DOI: 10.7270/Q2W66PDP
					More data for this Ligand-Target Pair