BDBM50465324 CHEMBL4286766
SMILES: [H][C@](O[C@@H]1O[C@H](CN)[C@@H](O)[C@H]1OC)([C@H](NCCCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)N[C@@H](C(C)C)C(O)=O)[C@]1([H])CCNC(=N)N1)[C@@H](O)C(C)C)C(O)=O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
InChI Key: InChIKey=GOFOFDWFFIGTML-IZAYEQDHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phospho-N-acetylmuramoyl-pentapeptide-transferase (Staphylococcus aureus (strain MRSA252)) | BDBM50465324 (CHEMBL4286766) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University of Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of Staphylococcus aureus MraY expressed in Escherichia coli membrane using Park's nucleotide as substrate pretreated for 30 mins followed ... | J Nat Prod 81: 942-948 (2018) Article DOI: 10.1021/acs.jnatprod.7b01054 BindingDB Entry DOI: 10.7270/Q2XS5Z1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospho-N-acetylmuramoyl-pentapeptide-transferase (Aquifex aeolicus (strain VF5)) | BDBM50465324 (CHEMBL4286766) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University of Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of Aquifex aeolicus MraY expressed in Escherichia coli C41(DE3) using Park's nucleotide as substrate pretreated for 30 mins followed by su... | J Nat Prod 81: 942-948 (2018) Article DOI: 10.1021/acs.jnatprod.7b01054 BindingDB Entry DOI: 10.7270/Q2XS5Z1V | |||||||||||
More data for this Ligand-Target Pair |