BDBM50465556 CHEMBL4283572

SMILES: Cc1cncc(c1)C(=O)NCc1cccc(c1)-c1cn2CCCc2n1

InChI Key: InChIKey=VDHLGRKJCUPRLS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50465556 (CHEMBL4283572) Show SMILES Cc1cncc(c1)C(=O)NCc1cccc(c1)-c1cn2CCCc2n1 Show InChI InChI=1S/C20H20N4O/c1-14-8-17(12-21-10-14)20(25)22-11-15-4-2-5-16(9-15)18-13-24-7-3-6-19(24)23-18/h2,4-5,8-10,12-13H,3,6-7,11H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	924	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to N-terminal 6x-His-SUMO tagged WDR5 delta23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli BL...				J Med Chem 61: 5623-5642 (2018) Article DOI: 10.1021/acs.jmedchem.8b00375 BindingDB Entry DOI: 10.7270/Q2KD21KT
					More data for this Ligand-Target Pair