BDBM50465601 CHEMBL4284629

SMILES: COc1cc(ccn1)C(=O)N(CC1CC1)Cc1cccc(c1)-c1cn2CCCc2n1

InChI Key: InChIKey=OTONOFNXSMNLHM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50465601 (CHEMBL4284629) Show SMILES COc1cc(ccn1)C(=O)N(CC1CC1)Cc1cccc(c1)-c1cn2CCCc2n1 Show InChI InChI=1S/C24H26N4O2/c1-30-23-13-20(9-10-25-23)24(29)28(14-17-7-8-17)15-18-4-2-5-19(12-18)21-16-27-11-3-6-22(27)26-21/h2,4-5,9-10,12-13,16-17H,3,6-8,11,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to N-terminal 6x-His-SUMO tagged WDR5 delta23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli BL...				J Med Chem 61: 5623-5642 (2018) Article DOI: 10.1021/acs.jmedchem.8b00375 BindingDB Entry DOI: 10.7270/Q2KD21KT
					More data for this Ligand-Target Pair