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BDBM50465923 CHEMBL4279018

SMILES: CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1cc2cnccc2cc1O

InChI Key: InChIKey=UISGQKNCYSNSMB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465923   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
1,3-beta-glucan synthase component GLS2


(Saccharomyces cerevisiae)		BDBM50465923
PNG
(CHEMBL4279018)
Show SMILES CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1cc2cnccc2cc1O
Show InChI InChI=1S/C23H29N5O/c1-22(2)12-17(13-23(3,4)27-22)28(5)21-7-6-19(25-26-21)18-10-16-14-24-9-8-15(16)11-20(18)29/h6-11,14,17,27,29H,12-13H2,1-5H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta counting

J Med Chem 61: 11021-11036 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01291
BindingDB Entry DOI: 10.7270/Q2474DJX
More data for this
Ligand-Target Pair