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BDBM50465924 CHEMBL4291213

SMILES: CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1ccc(cc1O)-n1cc(CO)cn1

InChI Key: InChIKey=HVYYWJDRZBFWQO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465924   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
1,3-beta-glucan synthase component GLS2


(Saccharomyces cerevisiae)		BDBM50465924
PNG
(CHEMBL4291213)
Show SMILES CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1ccc(cc1O)-n1cc(CO)cn1
Show InChI InChI=1S/C24H32N6O2/c1-23(2)11-18(12-24(3,4)28-23)29(5)22-9-8-20(26-27-22)19-7-6-17(10-21(19)32)30-14-16(15-31)13-25-30/h6-10,13-14,18,28,31-32H,11-12,15H2,1-5H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta counting

J Med Chem 61: 11021-11036 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01291
BindingDB Entry DOI: 10.7270/Q2474DJX
More data for this
Ligand-Target Pair