BDBM50466127 CHEMBL4288918

SMILES: COCCN1C=N\C(=C(\NCCN(C)C)c2cc3ccccc3[nH]2)C1=O

InChI Key: InChIKey=ONAJVJPZWSREGA-ISLYRVAYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50466127 (CHEMBL4288918) Show SMILES COCCN1C=N\C(=C(\NCCN(C)C)c2cc3ccccc3[nH]2)C1=O |c:5| Show InChI InChI=1S/C19H25N5O2/c1-23(2)9-8-20-17(16-12-14-6-4-5-7-15(14)22-16)18-19(25)24(13-21-18)10-11-26-3/h4-7,12-13,20,22H,8-11H2,1-3H3/b18-17+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Alcal£ Curated by ChEMBL					Assay Description Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysis				Eur J Med Chem 157: 946-959 (2018) Article DOI: 10.1016/j.ejmech.2018.08.045 BindingDB Entry DOI: 10.7270/Q29S1TQ2
					More data for this Ligand-Target Pair