Found 16 hits for monomerid = 50466530 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466530
(CHEMBL4281010)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C102H160N32O26/c1-6-54(3)81-96(156)129-74(50-78(106)141)93(153)124-67(91(151)132-82(55(4)7-2)97(157)134-83(56(5)136)98(158)126-69(22-17-45-118-102(111)112)87(147)125-70(36-38-77(105)140)89(149)123-68(21-16-44-117-101(109)110)88(148)130-75(99(159)160)48-59-28-34-63(139)35-29-59)19-11-14-41-114-79(142)39-37-71(121-84(144)64(104)46-57-24-30-61(137)31-25-57)90(150)131-76(52-135)95(155)122-65(18-10-12-40-103)85(145)115-42-13-8-9-23-80(143)120-66(20-15-43-116-100(107)108)86(146)128-73(49-60-51-113-53-119-60)92(152)127-72(94(154)133-81)47-58-26-32-62(138)33-27-58/h24-35,51,53-56,64-76,81-83,135-139H,6-23,36-50,52,103-104H2,1-5H3,(H2,105,140)(H2,106,141)(H,113,119)(H,114,142)(H,115,145)(H,120,143)(H,121,144)(H,122,155)(H,123,149)(H,124,153)(H,125,147)(H,126,158)(H,127,152)(H,128,146)(H,129,156)(H,130,148)(H,131,150)(H,132,151)(H,133,154)(H,134,157)(H,159,160)(H4,107,108,116)(H4,109,110,117)(H4,111,112,118)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Search and Browse
