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SMILES: [I-].C(CCOc1ccc(\C=C\c2ccccc2)cc1)CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=USACNLOFEZPZQN-OCOZRVBESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466610   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))		BDBM50466610
PNG
(CHEMBL4288506)
Show SMILES [I-].C(CCOc1ccc(\C=C\c2ccccc2)cc1)CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C37H36OP/c1-6-16-32(17-7-1)24-25-33-26-28-34(29-27-33)38-30-14-5-15-31-39(35-18-8-2-9-19-35,36-20-10-3-11-21-36)37-22-12-4-13-23-37/h1-4,6-13,16-29H,5,14-15,30-31H2/q+1/b25-24+
PDB

KEGG

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PC cid
PC sid
UniChem
Article
PubMed
 2.80E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Milano

Curated by ChEMBL


Assay Description
Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysis

J Med Chem 61: 10531-10544 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01052
BindingDB Entry DOI: 10.7270/Q2PV6P2W
More data for this
Ligand-Target Pair