null

SMILES: Cc1cc(C)n(n1)C(=O)c1ccc(o1)-c1ccc(F)cc1

InChI Key: InChIKey=JTUIOVFOUXJJDM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50466923 (CHEMBL4277735) Show SMILES Cc1cc(C)n(n1)C(=O)c1ccc(o1)-c1ccc(F)cc1 Show InChI InChI=1S/C16H13FN2O2/c1-10-9-11(2)19(18-10)16(20)15-8-7-14(21-15)12-3-5-13(17)6-4-12/h3-9H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate measured after 30 mins				Bioorg Med Chem Lett 28: 3276-3280 (2018) Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50466923 (CHEMBL4277735) Show SMILES Cc1cc(C)n(n1)C(=O)c1ccc(o1)-c1ccc(F)cc1 Show InChI InChI=1S/C16H13FN2O2/c1-10-9-11(2)19(18-10)16(20)15-8-7-14(21-15)12-3-5-13(17)6-4-12/h3-9H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 mins				Bioorg Med Chem Lett 28: 3276-3280 (2018) Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3
					More data for this Ligand-Target Pair