null

SMILES: Fc1ccc(cc1)-c1ccc(o1)C(=O)N1CCCc2ccccc12

InChI Key: InChIKey=GSPRYDOVENODIC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50466941 (CHEMBL4168223) Show SMILES Fc1ccc(cc1)-c1ccc(o1)C(=O)N1CCCc2ccccc12 Show InChI InChI=1S/C20H16FNO2/c21-16-9-7-15(8-10-16)18-11-12-19(24-18)20(23)22-13-3-5-14-4-1-2-6-17(14)22/h1-2,4,6-12H,3,5,13H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 3271-3275 (2018) Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50466941 (CHEMBL4168223) Show SMILES Fc1ccc(cc1)-c1ccc(o1)C(=O)N1CCCc2ccccc12 Show InChI InChI=1S/C20H16FNO2/c21-16-9-7-15(8-10-16)18-11-12-19(24-18)20(23)22-13-3-5-14-4-1-2-6-17(14)22/h1-2,4,6-12H,3,5,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 3271-3275 (2018) Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP
					More data for this Ligand-Target Pair