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SMILES: Cc1ccc(cc1)-c1ccc(o1)C(=O)N1CCc2ccccc2C1

InChI Key: InChIKey=CBLUFOBPNNUFOC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50466946 (CHEMBL4164011) Show SMILES Cc1ccc(cc1)-c1ccc(o1)C(=O)N1CCc2ccccc2C1 Show InChI InChI=1S/C21H19NO2/c1-15-6-8-17(9-7-15)19-10-11-20(24-19)21(23)22-13-12-16-4-2-3-5-18(16)14-22/h2-11H,12-14H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 3271-3275 (2018) Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50466946 (CHEMBL4164011) Show SMILES Cc1ccc(cc1)-c1ccc(o1)C(=O)N1CCc2ccccc2C1 Show InChI InChI=1S/C21H19NO2/c1-15-6-8-17(9-7-15)19-10-11-20(24-19)21(23)22-13-12-16-4-2-3-5-18(16)14-22/h2-11H,12-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 3271-3275 (2018) Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP
					More data for this Ligand-Target Pair